hrp0095p2-37 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

A rare case of childhood hypophosphatasia presenting with fibrous dysplasia

Jeon Jaesung , Lee Jun , Young Yoon Ju , Kun Cheon Chong

Objectives: Hypophosphatasia (HP) is a rare inherited disorder characterized by defective bone and teeth mineralization, and deficiency of serum and bone alkaline phosphatase activity. The symptoms are highly variable in their clinical expression, which ranges from stillbirth without a mineralized bone to early loss of teeth without bone symptoms. We aimed to report a patient with HP presenting with fibrous dysplasia.Methods:</st...